BALTIMORE (AP) — Miguel Andújar singled in the tiebreaking run in the ninth inning and the New York Yankees ran their winning streak against the Baltimore Orioles to 19 games with a 6-5 victory Friday in the opener of a doubleheader.

Gary Sanchez homered and Brett Gardner drove in two runs for the Yankees, who have won 18 in a row at Camden Yards — tied for the second-longest road streak in major league history by one team against another. The record is 19, by Brooklyn at Cincinnati from 1947-49.

Recalled from New York’s alternate site before the game, Andújar entered as a pinch-runner in the seventh and stayed in the game at third base. His single to right against Travis Lakins Sr. (2-2) made it 5-4, and Clint Frazier followed with an RBI single.

Jonathan Holder (2-0) worked the eighth and Chad Green got three outs for his first save. Holder ran for himself after New York burned the designated hitter and scored on Andújar’s single.

Facing the Orioles probably couldn’t have come at a better time for the Yankees, who had lost three of four and 10 of 14. The latter slide followed a 16-6 start and dropped New York out of first place in the AL East.

Cedric Mullins hit a leadoff homer for the Orioles, who erased a three-run deficit behind long balls by Rio Ruiz and Renato Núñez.

BLUE JAYS 8, RED SOX 7, 1st game

RED SOX 3, BLUE JAYS 2, 2nd game

Yairo Muñoz had three hits and Boston salvaged a spit of their doubleheader as the “road” team at Fenway Park to end a five-game losing streak.

Muñoz went 6 for 7 in the twinbill with a two-run homer, two doubles and three RBIs.

Toronto was the “home” team in the second game, which was the makeup of the Aug. 27 game in Buffalo, New York, that was postponed when the teams didn’t play in protest over the shooting by police of Jacob Blake.

Rowdy Tellez hit a solo homer for the Blue Jays, who had won seven of nine after taking the opener.

Josh Taylor (1-1) pitched a scoreless inning of relief for the win. Matt Barnes got the final three outs for his fourth save. Making his first start for Toronto since being acquired from the Dodgers for two players to be named, Ross Stripling (3-2) gave up three runs in 4 1/3 innings.

In the opner, Danny Jansen hit a two-run homer, Travis Shaw had a solo shot and the Blue Jays held n.

Muñoz went 3 for 3 with a two-run homer and an RBI double. A.J. Cole (2-0) pitched an inning of scoreless relief and Anthony Bass got three outs for his fifth save. Zack Godley (0-4) was the loser.

PHILLIES 5, METS 3

NEW YORK (AP) — Jake Arrieta bounced back from the shortest start of his career by pitching seven solid innings to lead Philadelphia past New York for its fifth straight win.

Roman Quinn snapped a tie with a two-out, RBI single in the seventh.

The Mets wore patches with No. 41 on the uniform sleeves in honor of Hall of Fame pitcher Tom Seaver, who died this week.

Arrieta (3-4), who gave up seven runs in 1 1/3 innings against Atlanta on Sunday, allowed two runs and seven hits while walking one and striking out seven.

Jay Bruce and Didi Gregorius had early RBIs to stake Arrieta to a 2-0 lead. Michael Conforto hit a tying, two-run homer in the fifth before Arrieta retired six of the final seven batters he faced.

The Phillies put Arrieta in line for the win in the seventh. Jared Hughes (1-2) retired the first two batters he faced before Phil Gosselin doubled and scored on Quinn’s hit.

CUBS 4, CARDINALS 1

CHICAGO (AP) — Yu Darvish pitched seven dazzling innings in his seventh consecutive win and Chicago beat St. Louis in the opener of a big five-game series.

Led by Darvish and Willson Contreras, Chicago won for the fourth time in five games and strengthened its grip on the top spot in the NL Central. St. Louis dropped into a virtual tie with Milwaukee for second, 4 1/2 games back of the Cubs.

Contreras had three hits and four RBIs, including a leadoff drive in the sixth for his fifth homer. He also had a big two-run single on the ninth pitch of his at-bat against Jack Flaherty (2-1) in the first.

Darvish (7-1) was working on a perfect game before Matt Carpenter opened the sixth with his second homer, a drive to the basket in right-center on the ninth pitch of the at-bat. The Japanese right-hander then retired his last six batters, striking out three more to give him 11 on the night.

Rowan Wick worked the eighth, and Jeremy Jeffress finished the two-hitter for his fifth save.

RAYS 5, MARLINS 4

ST. PETERSBURG, Fla. (AP) — Rookie left-hander Josh Fleming won his third consecutive start, Michael Perez had a three-run double and AL East-leading Tampa Bay beat Miami.

Yoshi Tsutsugo homered for the Rays, who have won 20 of 25. Tampa Bay has a nine-game winning streak against Miami.

The Marlins got homers from Corey Dickerson and Jesús Aguilar.

Fleming (3-0) allowed four runs and seven hits over five innings in joining Jake Faria (2017) and Jeremy Hellickson (2010) as the only Rays pitcher to win their first three major league starts.

Nick Anderson, the fourth Tampa Bay reliever, worked out of a two-on, no-out jam in the ninth to get his fourth save. Pablo López (3-3) was the loser.

BRAVES 7, NATIONALS 1, 1st game

NATIONALS 10, BRAVES 9, 2nd game

ATLANTA (AP) — Trea Turner gave Washington the lead with a sixth-inning home run off Will Smith and the Nationals held on in the seventh to beat Atlanta Braves and split a doubleheader.

Ronald Acuña Jr. homered twice and Dansby Swanson added a two-run shot for the Braves in the opener. Acuña hit three home runs in the doubleheader.

The defending World Series champion Nationals ended a seven-game losing streak and snapped the NL East-leading Braves’ streak of five consecutive wins.

Travis d’Arnaud hit a two-run homer in the seventh inning of the second game off Nationals closer Daniel Hudson. Wander Suero (2-0) had two strikeouts in a perfect fifth inning. Smith dropped to 2-1.

In the opener, Darren O’Day (3-0) pitched a scoreless fifth. Austin Voth (0-5) was the loser.

TWINS 2, TIGERS 0, 1st game

TWINS 3, TIGERS 2, 8 innings, 2nd game

MINNEAPOLIS (AP) — Marwin Gonzalez singled home Willians Astudillo in the eighth inning, and Minnesota rallied to beat for a doubleheader sweep.

Astudillo started on second base with the eighth inning considered an extra-inning due to the seven-inning doubleheader rule. Gonzalez hit a grounder up the middle and Detroit center fielder Derek Hill, making his major league debut, bobbled the ball, allowing Astudillo to score easily.

Sergio Romo (1-1) pitched a perfect seventh and Trevor May picked up his second save in four chances as Minnesota won its fourth straight game. Joe Jimenez (1-3) allowed Gonzalez’s hit to take the loss after Gregory Soto blew a save in the seventh.

In the opener, Polanco and Josh Donaldson hit back-to-back homers to lead off the bottom of the first inning, and Randy Dobnak (6-2) bounced back with five scoreless innings. Matt Boyd (1-5) allowed consecutive leadoff homers for the third time in less than a month. He also gave up back-to-back home runs to the Chicago White Sox to start games Aug. 12 and 17.

REDS 4, PIRATES 2, 1st game

PIRATES 4, REDS 3, 2nd game

PITTSBURGH (AP) — Pittsburgh took advantage of an uncharacteristically average performance by Cincinnati’s Trevor Bauer to split a doubleheader.

The Reds took the opener behind Luis Castillo, who picked up his first victory in nearly a year when he worked six solid innings. Cincinnati, however, missed a chance to sweep a doubleheader for the third time this season when the Pirates scrounged up just enough offense against Bauer.

Recently acquired outfielder Anthony Alford hit a two-run triple off Bauer in the fourth and tied it when Bauer’s second wild pitch of the season briefly skipped out of reach of catcher Tucker Barnhart.

Bauer (3-3) allowed four runs but his ERA actually dropped from 2.13 to 2.05 after an error by first baseman Joey Votto that opened up the door for three unearned runs to cross the plate in the fourth. Bauer surrendered six hits against two walks and seven strikeouts.

Sam Howard (2-1) picked up the win in relief. Richard Rodriguez worked a perfect seventh for his third save.

In the opener, Castillo (1-5) struck out eight and walked two to earn his first win since Sept. 13, 2019. A 15-game winner and an All-Star last season, he had dropped seven straight decisions. Nick Castellanos hit his 11th home run for the Reds, a solo shot off Steven Brault (0-2).

BREWERS 7, INDIANS 1

CLEVELAND (AP) — Corbin Burnes pitched six strong innings, Keston Hiura hit an RBI double in Milwaukee’s four-run seventh inning and the Brewers scored three times on two weak infield grounders.

Burnes (2-0) didn’t allow an earned run and only three hits to offensively inconsistent Cleveland, which had just four hits. He recently returned to the rotation after a three-game relief stint and had his second straight solid outing.

Hiura added a two-run homer in the seventh for the Brewers.

Phil Maton (2-1) took the loss.